Clinicopathologic study of triple-negative breast cancer with special reference to basal-like breast cancer phenotype in a tertiary care hospital of Eastern India

Background: Triple-negative breast cancer (TNBC) is defined as absent expression of estrogen receptor (ER) and progesterone receptors human epidermal growth factor (HER2neu). These cancers are associated with poor prognosis. Aims Objectives: We aimed at to study the clinicopathological profile survival among women TNBC. Materials Methods: The was conducted over a period 4 years. Surgical specimens patients were analyzed histopathologically well immunohistochemical analysis for estrogen, progesterone, HER2neu, Ki-67 index also done. Statistical done using software version 20.0. Results expressed in number percentage. Comparison by x2 test. P=0.05 considered statistically significant. Results: In our study, 26.92% cases Predominant age group affected between 50 70 Most common histologic type invasive carcinoma no special higher grade (Grades 2 3) mostly frequent nodal metastasis. Higher percentage proliferation basal cytokeratin tumor stage along reduced short-term disease-free on follow-up. Conclusion: TNBCs usually recurrences distant There widely accepted prognostic markers available. Panel should be used specially categorize basal-like subtype better clinical outcome.